Publish In |
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT |
Journal Home Volume Issue |
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Issue |
Volume-6, Issue-4, Spl. Iss-1 ( Nov, 2018 ) | |||||||||
Paper Title |
Theoretical Study of the Alzheimer Drug Posiphen by Molecular Modeling Methods | |||||||||
Author Name |
I. Abdelli, I. Daoud, M. Merad, S. Ghalem | |||||||||
Affilition |
Higher School of Applied Sciences- Tlemecen-Algeria, Laboratory of Natural and bio-actives Substances .Tlemcen University- Faculty of Science. P.O.Box 119-Tlemcen-Algeria. University Mohamed Khider, Department of Matter Sciences, BP 145 RP; 07000, Biskra, Algeria. | |||||||||
Pages |
90-93 | |||||||||
Abstract |
Neurodegenerative diseases comprise one of the major public health concerns in our aging population. Alzheimer’s disease (AD) is the case, the most common form of dementia, is a degenerative disorder of the brain that leads to memory loss. The accumulation of β-amyloid is the most important factor for this disease. Our work propose theoretical study the inhibition of β-secretase enzyme wich is responsible from the accumulation of the β-amyloid by molecules serie supposed a based for posiphen as remedy of the Alzheimer disease. Key words - Alzheimer disease, posiphen drugs, molecular modeling methods. | |||||||||
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