DOIONLINE

DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-4466

Publish In
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT
Journal Home
Volume Issue
Issue
Volume-4,Issue-2  ( Apr, 2016 )
Paper Title
The Application Of Models To The Micrornas Mediated Viral Oncogenesis
Author Name
Sathishkumar.K, Prabakar.P, John.M
Affilition
Institute of Molecular Biology, C-21, Taramani CSIR Road, Chennai – 600 113, India.
Pages
32-36
Abstract
Micro RNAs are a recently discovered class of small non coding functional RNAs. These molecules mediate posttranscriptional regulation of gene expression in a sequence specific manner. Micro RNAs are now known to be key players in a variety of biological processes and have been shown to be deregulated in a number of cancers. The discovery of viral encoded micro RNAs, especially from a family of oncogenic viruses, has attracted immense attention towards the possibility of micro RNAs as critical modulators of viral oncogenesis. The host-virus crosstalk mediated by micro RNAs, messenger RNAs and proteins, is complex and involves the different cellular regulatory layers. In this commentary, we describe models of microRNA mediated viral oncogenesis
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