DOIONLINE

DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-3593

Publish In
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT
Journal Home
Volume Issue
Issue
Special Issue-5,  ( Dec, 2015 )
Paper Title
Paper-Based Electrochemical Biosensor For Glucose Detection
Author Name
Chang Bing Tao, Ching-Shu Yen, Shu-Ying Chen, Shwu-Jen Chang, Jen-Tsai Liu, Ching-Jung Chen
Affilition
College of Materials Science and Opti-Electronic Technology, University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China Department of Biomedical Engineering, I-SHOU University, No.8, Yida Rd., Yanchao District, Kaohsiung City 82445, Taiwan, R.O.C School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China
Pages
1-4
Abstract
In this work, an innovative, low cost and biodegradable paper-based electrochemical biosensor for the determination of glucose is reported. The novel biosensor was fabricated by immobilizing glucose oxidase(GOx) on screen printed carbon electrodes. The electrochemical behavior of the biosensor was studied using cyclic voltammetry(CV), showing that the developed biosensor possessed high heterogeneous electron transfer rate constant(1.72×10- 3).Thebiosensorexhibited good amperometric responsestoward glucose, with a wide linear range up to 10 mM with R2is 0.98 and the sensitivity is 0.68μA mM−1. The parallel measurements of 5mM glucose by eight different sensors had a low relative standard deviation of 5.56%, suggesting its good reproducibility. In the interference studies, there wasno significant difference after addition ofascorbic acid or uric acid. It retained 94.6% of its initialresponse after a storage period of ten days in 4°C, indicating that thispaper-based electrochemical biosensor had good stability. Keywords - Paper-Based Electrochemical Biosensor, Screen Printed Carbon Electrode, Glucose Oxidase, Glucose.
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