DOIONLINE

DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-20520

Publish In
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT
Journal Home
Volume Issue
Issue
Volume-12,Issue-1  ( Jan, 2024 )
Paper Title
Particle Simulation of Skin Formation: Relationship Between Skin Homeostasis and Bound Water
Author Name
Katsuya Nagayama, Shu Oba
Affilition
Pages
47-50
Abstract
As the epidermis adapts to different environments, the desquamation of keratinocytes is affected by the water content of the epidermis. The thickness of the stratum corneum is determined by the interaction between exfoliation and water content. The balance between these processes is the key to healthy skin. In this study, a numerical model of stratum corneum thickness was constructed based on the interaction between exfoliation and water content. In this model, free water on the skin surface is removed, and skin homeostasis is expressed by focusing on the differences in the amount of bound water. This numerical simulation presents that when the skin is dry, keratin tends to increase because of the regulation mechanism; however, when the skin is too dry, the accumulated keratin clumps up and easily peels off. Keywords - Particle simulation, Skin, Stratum corneum, Homeostasis, Bound water.
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