DOIONLINE

DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-14425

Publish In
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT
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Volume Issue
Issue
Volume-6, Issue-4, Spl. Iss-1  ( Nov, 2018 )
Paper Title
Theoretical Study of the Alzheimer Drug Posiphen by Molecular Modeling Methods
Author Name
I. Abdelli, I. Daoud, M. Merad, S. Ghalem
Affilition
Higher School of Applied Sciences- Tlemecen-Algeria, Laboratory of Natural and bio-actives Substances .Tlemcen University- Faculty of Science. P.O.Box 119-Tlemcen-Algeria. University Mohamed Khider, Department of Matter Sciences, BP 145 RP; 07000, Biskra, Algeria.
Pages
90-93
Abstract
Neurodegenerative diseases comprise one of the major public health concerns in our aging population. Alzheimer’s disease (AD) is the case, the most common form of dementia, is a degenerative disorder of the brain that leads to memory loss. The accumulation of β-amyloid is the most important factor for this disease. Our work propose theoretical study the inhibition of β-secretase enzyme wich is responsible from the accumulation of the β-amyloid by molecules serie supposed a based for posiphen as remedy of the Alzheimer disease. Key words - Alzheimer disease, posiphen drugs, molecular modeling methods.
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