DOIONLINE

DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-12202

Publish In
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT
Journal Home
Volume Issue
Issue
Volume-6, Issue-2, Spl. Iss-1  ( May, 2018 )
Paper Title
Type VI Secretion System: A syringe for survival
Author Name
Abhishek Prasad
Affilition
Department of Biological Sciences, Birla Institute of Technology and Sciences, Pilani, India
Pages
32-38
Abstract
Bacterial Type VI Secretion Systems (T6SS) have a bacteriophage needle – like structure used to puncture target cells and deliver effectors subverting the outer membranous layer of the target cells. Within ten years since its discovery, the T6SS apparatus has been duly researched and documented. Its core components and effectors have been identified and ascribed specific functions. Utility of the T6SS in pathogenicity and inter-bacterial interactions have been studied great detail. This review covers the milestone discovery of the T6SS apparatus, an overview of its gene locus, proposed structure and core components. We also delve into the utility of T6SS apparatus in bacterial pathogenicity, sustenance, inter-bacterial interactions, communal behavior and bacterial fitness. Index Terms - Bacterial secretion system, bacterial fitness, contact dependent, Hcp, phage-like machinery, VgrG.
  View Paper