DOIONLINE 
DOIONLINE Publish In |
International Journal of Advances in Science, Engineering and Technology(IJASEAT)-IJASEAT |
 Journal Home Volume Issue |
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Issue |
Volume-6, Issue-1 ( Jan, 2018 ) | |||||||||
Paper Title |
Expedient Synthesis and Organocatalytic Studies of Enantiomerically Enriched Benzimidazole-Triazoles | |||||||||
Author Name |
Jai V. Sapre, Vaibhav N. Khose, Anil V. Karnik | |||||||||
Affilition |
Department of Chemistry, University of Mumbai, Vidyanagari, Mumbai 400 098 | |||||||||
Pages |
42-49 | |||||||||
Abstract |
Click chemistry induced synthesis of highly enantiomerically enriched 4-(benzimidazolylmethyl)-1,2,3-triazole derivatives 8(a-g) and 9(a-g) has been achieved. These compounds are bestowed with flexibly bound pi-rich hetero-aryl rings, many binding sites and nucleophilic nitrogens in the vicinity of a chiral center. The synthesis is high yielding and regioselective. The synthesized chiral benzimidazole-triazoles have been found useful as the organocatalyst for the enantioselective Diels-Alder (DA) reaction between anthrone (10) and maleimide detivatives 11(a-g). Enantioselectivity levels were found to be dependent on several factors including nature of substituents in benzimidazole-triazoles 8(a-g) and 9(a-g). Index Term- Enantiomerically enriched, click chemistry, tweezer, benzimidazole-triazoles, Diels Alder Adduct | |||||||||
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